Applications

Our core competencies span a wide range of lifescience niches, such as Personalised Medicine & Healthcare (e.g. home diagnostic kits), Biomedical Diagnostics (e.g. COVID testing), technologies for Pharmaceutical Production (e.g. novel cancer biomarkers & drugs), and Environmental Testing (e.g. water and/or foodstuffs quality). We cater for all Technology Readiness Levels (TRLs) but with a keen focus on translation of early stage concepts with a multi-disciplinary origin.

How We Work

1.

1. Conceptualise & Design
1. Conceptualise & Design

Centrifugo-Magnetophoresis Capture entity functionalized magnetic particles integrated into a microfluidic system inherent advantage is the ability to both aggregate and mix/disperse particles using simple automated motor actuation Optical path clarity operations Routing of Assay liquid components

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2. Develop technology
2. Develop technology

Centrifugo-Pneumatic DF Valving Ancillary liquid controls gating of main liquid (sample or reagents) Cascading, event triggered valving

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3. Manufacture prototype
3. Manufacture prototype

Event-Triggered Flow Control Serial siphoning of highly accurate aliquots Allows for user and instrument independent valving and flow control that can be “hard wired” into the microfluidic platform

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4. Automate assembly line for scalability
4. Automate assembly line for scalability

Automated pick and plan assembly line Automated and scaleable manufacture of microfluidic device incorporating on-disc operations currently impossible to mass manufacture using injection molding Precision assembly that is highly repeatable and easily scaleable and incorporated within your existing fabrication process

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A wide range of industrial sectors with needs for decentralised bioanalysis can benefit from the services provided by the Microfluidics Centre Dublin. Some examples of where this technology has been applied is listed below:​​​

  • Cell line development & optimisation

  • Single use technologies

  • Continuous manufacturing

  • Regulatory requirements

  • Process Analytical Technologies

  • Detection of diseases – infectious, autoimmune, cancer, cardiovascular and sexually transmitted diseases

  • Prenatal screening

  • HIV and syphilis testing

  • Detection of influenza and airborne diseases (e.g. Covid-19)

  • Device bioanalytical capabilities

  • Detection of food-borne pathogens

  • Detection of fraudulent substances in animal feed or in animal products

  • Nano-particle encapsulation of fish oil

  • Monitoring pathogens and toxins in food and water supplies

  • Micro-nano-filtration for improving food quality

  • Detection of antibiotics in dairy food products

  • Generation of novel food structures

  • Rapid detection and identification of compounds

  • Water quality testing

  • Detection of emerging and exotic diseases

  • Detection of OIE-listed diseases (e.g. foot & mouth)

  • Detection of food borne pathogens

  • Detection fo fraudulent subtances in feed

  • Detection fo ketosis in cattle